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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCCC2 All Species: 26.06
Human Site: S328 Identified Species: 47.78
UniProt: Q9HCC0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HCC0 NP_071415.1 563 61333 S328 V G A N L K R S F D V R E V I
Chimpanzee Pan troglodytes XP_517717 563 61220 S328 V G A N L K R S F D V R E V I
Rhesus Macaque Macaca mulatta XP_001096794 563 61647 N328 V G A N L K R N F D V R E V I
Dog Lupus familis XP_535268 563 61534 Q328 V G T N L K R Q F D V R E V I
Cat Felis silvestris
Mouse Mus musculus Q3ULD5 563 61361 S328 V G A N L K R S F D V R E V I
Rat Rattus norvegicus Q5XIT9 563 61499 S328 V G A N L K R S F D V R E V I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001091355 562 61332 N327 V G A N L K K N F D V R E V I
Zebra Danio Brachydanio rerio NP_998092 566 61725 N331 V G D N L K R N F D I R E V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9A7 578 62630 S343 V G P N L T K S F D V R E V I
Honey Bee Apis mellifera XP_394033 559 61367 T324 V G L N W K Q T Y D V R E V I
Nematode Worm Caenorhab. elegans P34385 608 66505 T373 V G S N L K K T Y D V R E V I
Sea Urchin Strong. purpuratus XP_001201046 552 59601 V317 A S V D F S K V Y D I R E V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDD8 587 63994 P346 N E L R S I A P V D H K Q Q F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93 87.9 N.A. 88.8 88.2 N.A. N.A. N.A. 81.5 81 N.A. 67.4 69 59.2 65.5
Protein Similarity: 100 99.1 95.3 93.7 N.A. 94.3 94.3 N.A. N.A. N.A. 90.4 89.2 N.A. 78.7 82.5 74.5 79.5
P-Site Identity: 100 100 93.3 86.6 N.A. 100 100 N.A. N.A. N.A. 86.6 80 N.A. 80 66.6 73.3 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 100 100 N.A. N.A. N.A. 100 93.3 N.A. 86.6 86.6 100 60
Percent
Protein Identity: N.A. N.A. N.A. 58 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 73 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 47 0 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 0 0 0 100 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 93 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 70 0 0 0 0 0 8 % F
% Gly: 0 85 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 16 0 0 0 93 % I
% Lys: 0 0 0 0 0 77 31 0 0 0 0 8 0 0 0 % K
% Leu: 0 0 16 0 77 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 85 0 0 0 24 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 8 0 0 0 0 8 8 0 % Q
% Arg: 0 0 0 8 0 0 54 0 0 0 0 93 0 0 0 % R
% Ser: 0 8 8 0 8 8 0 39 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 0 8 0 16 0 0 0 0 0 0 0 % T
% Val: 85 0 8 0 0 0 0 8 8 0 77 0 0 93 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 24 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _